Live While We're Young

We're all living in the same apartment as One Direction...what could possibly go wrong?

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can I reserve zayn's gf I can have it up tonight or tmmorrow

jackrules158

Member for 3 years

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May I reserve Niall's girlfriend and have her as Louis' sister? I can have her up shortly. :)

~ wanderer.

Wanderer

Member for 1 years

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Norwegian targets global business travel growth with Sabre | News ...

Sabre Travel Network has signed a multi-year agreement with Norwegian to sell its fares, schedules and inventory to Sabre-connected travel agencies.

As part of the agreement, travel agents will be able to shop for and book tickets that include ancillary services offered by the carrier, including on-board meals and up to two checked bags.

Lars Sande, sales director for Norwegian said: ?This agreement with Sabre, and the global reach it provides, will help distribute our product into new markets.

?The agency channel will play a crucial role in our ability to provide a first-rate travel experience at affordable prices to the broadest possible customer base.

?It will also allow agencies and travel management companies to efficiently shop and book our bundled fares.?

The deal with Sabre is part of Norwegian?s long-term growth strategy that includes entry in to the North American marketplace.

Harald Eisenaecher, senior vice president for Sabre EMEA, said: ?Norwegian?s importance among European corporations and business travellers has been growing in recent years.

?Sabre aims to play a pivotal role in the airline?s future by making its fares, ancillaries and schedules available to our global travel agency community and helping drive revenue from the corporate market.

?We will continue to invest in the products and services that low-cost carriers, such as Norwegian, need to grow their international businesses.?

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Source: http://www.breakingtravelnews.com/news/article/norwegian-targets-global-business-travel-growth-with-sabre/

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Quantum dots deliver vitamin D to tumors for possible inflammatory breast cancer treatment

Feb. 1, 2013 ? The shortened daylight of a Maine winter may make for long, dark nights -- but it has shone a light on a novel experimental approach to fighting inflammatory breast cancer (IBC), an especially deadly form of breast cancer.

The new approach enlists the active form of Vitamin D3, called calcitriol, which is delivered therapeutically by quantum dots. Quantum dots are an engineered light-emitting nanoscale delivery vehicle. This new preliminary work shows the dots can be used to rapidly move high concentrations of calcitriol to targeted tumor sites where cancer cells accumulate, and also through the lymph system where the cancer spreads. With this approach, the calcitriol can fight on multiple fronts and the targeted location can be visualized with an imaging system tracking the quantum dots.

The research will be presented at the 57th Annual Meeting of the Biophysical Society (BPS), held Feb. 2-6, 2013, in Philadelphia, Pa.

University of Delaware cancer researcher Anja Nohe was living in Maine when she first received funding from the Maine Cancer Foundation to determine the effect of calcitriol on breast cancer cells. Reading cancer literature helped her make connections between cancer, vitamin D, and the daylight regime of higher latitudes. "By talking with talented colleagues about these ideas, the foundation was set for the current project," she says. After moving to the University of Delaware, she began working with Kenneth Van Golen, "an expert in the biology of IBC," to evaluate calcitriol.

Compared to other forms of breast cancer, IBC is especially difficult to treat. It has a five-year survival rate of 40% versus 87% for all other breast cancers. A big part of what makes IBC treatment difficult is its multi-site growth pattern. Current aggressive treatments such as combinations of chemotherapy, surgery and radiation, have failed to significantly improve IBC survival rates.

This early experimental work on mice is encouraging because data show calcitriol can inhibit invasion and migration of SUM149 cells, an IBC cell line. "New IBC therapies are urgently needed, which is why the goal of my work is to find a successful treatment for inflammatory breast cancer, especially one with fewer side effects," Nohe says.

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The above story is reprinted from materials provided by Biophysical Society, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/PVNxA6Z0mnE/130201095955.htm

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Clinton's Exit: Either Epilogue or Prelude (WSJ)

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Investing in UK prosperity: skills, infrastructure and innovation can ...

The latest GDP figures confirm that the UK economy has essentially been flat-lining for the five years since the financial crisis began. The UK?s inability to achieve sustainable growth is rooted in longer-term problems arising from a failure to invest, notably in skills, infrastructure and innovation. Timothy Besley?and?John Van Reenen, co-chairs of the London School of Economics Growth Commission, which publishes its final report today, propose an integrated set of solutions.

The outlook for the UK economy looks bleak even for a British winter with output depressed for a longer period than even during the Great Depression. The institutions of UK economic policy-making seem unable to steer the economy out of nearly five years of stagnation and into a sustainable recovery.?While the specific issues vary country-by-country, this theme resonates across the advanced world with output below potential and unemployment generally high. The spectre of Japan?s two ?lost decades? following an asset crash casts a shadow over much policy debate.

The LSE Growth Commission, which we have co-chaired, is a collaborative effort drawing on academic, business and policy-making expertise. Its aim has been to develop an evidence-based approach to policy over the long term. And the perspective also takes politics seriously, focusing on the structures that are needed to support growth policy beyond the next budget cycle, the next spending review and the next parliament.

The UK?s economic story

It is sometimes remarked that the British are the only people who indulge in Schadenfreude about themselves, revelling in stories of national decline. This is perhaps the inevitable legacy of being the first industrial nation. Although the UK has enjoyed significant improvements in material wellbeing for well over two centuries, UK GDP per capita was in relative decline compared with other leading countries, such as France, Germany and the US, from around 1870.

At first, the UK?s relative decline reflected an almost inevitable catch-up of other countries whose institutions created the right kind of investment climate. But by the late 1970s, as the UK had been comprehensively overtaken: US GDP per capita was about 40% higher than the UK?s and the major continental European countries were 10-15% ahead. The subsequent three decades, in contrast, saw the UK?s relative performance improve substantially so that by the eve of the crisis in 2007, UK GDP per capita had overtaken both France and Germany and reduced significantly the gap with the US. Figure 1 shows trends in UK GDP per capita since 1950. After falling behind for most of the post-war period, the UK had a better performance compared with other leading countries after the 1970s.

Figure 1: GDP per capita 1950-2011 (1980=100)

Notes: GDP is US$, constant prices, constant PPPs, base year 2011. For each country the series is set to one hundred in 1980, so the level of the line in any year indicates the cumulative growth rate (for example, a value of 110 in 2001 indicates that the series has grown by 10% between 1980 and 2001). The steeper the slope of the line, the faster growth has been over that period.

Source: Conference Board data, LSE Growth Commission

A range of important policy changes underpinned these economic gains (see, for example, Corry, Valero and Van Reenen, 2011; Card, Blundell and Freeman, 2004; OECD, 2012). These include increases in product market competition through the withdrawal of industrial subsidies, a movement to effective competition in many privatised sectors with independent regulators, a strengthening of competition policy and our membership of the European Union?s internal market.

There were also increases in labour market flexibility through improving job search for those on benefits, reducing replacement rates, increasing in-work benefits and restricting union power. The UK was open to foreign business and global talent: restrictions on foreign direct investment were eased in the 1980s and restrictions on immigration relaxed in the late 1990s. And there was a sustained expansion of the higher education system: the share of working age adults with a university degree rose from 5% in 1980 to 14% in 1996 and 31% in 2011, a faster increase than in France, Germany or the US.

In some policy areas, the UK has also led the way in seeking innovative institutional solutions, such as independent regulators, for designing and implementing policy more effectively. This created a better balance between political discretion, technocratic input and predictable rules. Strategic choices, rules and high-level objectives are set by government while independent bodies make decisions based on the criteria laid down by politicians and are held to account by parliament. This has mitigated the problems of political indecision and unpredictability that are important impediments to investment and growth.

In spite of these policy successes, a number of long-term investment failures have not been tackled. The most important of these are a failure to invest in mid-level skills, a failure to build adequate infrastructure ? particularly in transport and energy ? and a failure to provide a supportive environment for private investment and innovation. These problems have persisted due to the absence of a stable policy framework backed by a cross-party consensus in these areas.

Policy reforms for growth

The reforms that we propose are aimed at tackling these problems. First, for human capital, where the UK suffers from a stronger link between parental income and pupil performance than other countries, we propose:

• Improving teacher quality through expanding the intake of teachers and engaging in more rigorous selection. This is because ex ante evaluation of teacher quality is hard, but ex post evaluation easier.
• Creating a ?flexible ecology? by which we mean more autonomous primary and secondary schools, greater parental choice and easier growth for successful schools and their sponsors (for example, universities or educational networks).
• Linking targets, inspections and rewards more effectively to hold schools to account for the outcomes of disadvantaged pupils.

We propose developing a new institutional architecture to address the poor quality of our national infrastructure. This would dramatically reduce the policy instability that arises from frequent changes in political personnel and priorities, particularly in transport and energy:

• An Infrastructure Strategy Board to provide independent expert advice to parliament to guide strategic priorities.
• An Infrastructure Planning Commission to support the implementation of those priorities with more powers to share the gains from infrastructure investment by more generously compensating those who stand to lose from new developments.
• An Infrastructure Bank to facilitate the provision of finance, to bring in expertise and to work with the private sector to share, reduce and manage risk.

We propose improving the provision of finance for private investment and innovation through:

• Increasing competition in retail banking.
• Having the proposed Business Bank make young and innovative firms its top priority.
• Encouraging a long-term investment perspective through regulatory changes (for example, over equity voting rights) and tax reforms (for example, reducing the bias towards debt finance through an ?allowance for corporate equity?).

Prosperity is strengthened when everyone has the capacity to participate effectively in the economy and the benefits of growth are widely shared. We propose reforming the way we measure and monitor changes in material wellbeing and its distribution, including regularly publishing median household income alongside the latest data on GDP.

Our core proposals can provide the stable policy framework that has long been lacking in the UK, one that will encourage long-term investment. By ensuring that difficult and contentious long-term decisions are based on the best available independent expertise, they would help to break the damaging cycle of institutional churn, political procrastination and policy instability.

The principle that policy should be evidence-based is now widely accepted, but often more in word than deed. Many of the areas where there are potential benefits to growth are largely untested. The benefits to long-term growth from properly conducted policy experiments in some areas could be significant while the costs of experimentation are modest. We therefore recommend creating an independent National Growth Council to review relevant evidence and to recommend growth-enhancing policy reforms that could be subject to rigorous evaluation.

Whether the LSE Growth Commission is successful in influencing the direction of policy remains to be seen. But we believe it offers a template for the engagement of academics in these important policy debates. The engagement with policy will not end with the report ? the aim now is to try to build the consensus around a manifesto for growth. The challenge has never been greater given the pressures that mature economies are facing from international competition and a myriad of changes in the world.

Note: This article gives the views of the?author, and not the position of the British Politics and Policy blog, nor of the London School of Economics.?Please read our?comments policy?before posting.

About the authors

Timothy Besley is Professor of Economics and Political Science?at the London School of Economics.

John Van Reenen?is Director of the Centre for Economic Performance and a Professor at the London School of Economics

You may also be interested in the following posts (automatically generated):

1. The UK?s sustained growth between 1997 and 2008 was fuelled by the importance of skills and new technology. Rather than just austerity, the government should focus on building human capital and innovation to support long-term growth.
2. Private financing for public infrastructure is here to stay despite ?PFIs? being consigned to history
3. Restoring growth and confidence through resource-efficient innovation
4. How to get prosperity with growth (green growth that is)

Source: http://blogs.lse.ac.uk/politicsandpolicy/archives/30368

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Ronaiah Tuiasosopo: Hoping to "Recover" from Homosexuality

Source: http://www.thehollywoodgossip.com/2013/01/ronaiah-tuiasosopo-hoping-to-recover-from-homosexuality/

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Hispanic Leadership Network To Politicians: Don't Call Immigrants ...

Will the revitalized immigration debate change the language politicians use?

Organizations and advocates including journalist Jose Antonio Vargas, the publication Colorlines, and the National Association of Hispanic Journalists have tried to convince mainstream media to drop the term ?illegal immigrant,? saying it criminalizes people rather than their actions.

And now a center-right political organization is pushing conservatives to do the same.

The Hispanic Leadership Network sent around a ?Dos and Don?ts of Immigration Reform? to politicians this week. It contains common-sense advice for those looking to discuss immigration without offending the sensibilities of Latino voters, 90 percent of whom support the DREAM Act and 85 percent of whom favor a pathway to citizenship for the undocumented, according to a Fox News Latino poll conducted last year.

?Do use ?undocumented immigrant? when referring to those here without documentation,? the memo recommends. ?Don?t use the word ?illegals? or ?aliens.? Don?t use the term ?anchor baby.??

The Hispanic Leadership Network has a compelling reason to urge politicians to adopt such language when discussing immigration: the same Fox News Latino poll found that 46 percent of Hispanic voters find the term ?illegal immigrant? offensive. There are also new questions about the term?s accuracy, now that a class of undocumented immigrants is permitted to stay legally in the United States under President Obama?s June directive to defer deportation for childhood arrivals.

The message falls on deaf ears for some. Executive Director of the Center for Immigration Studies, who backs stricter immigration enforcement, dismissed the suggestion on Twitter:

The point was also lost on congressmen like Rep. Lou Barletta (R-Pa.), who is actively pushing away the Latino vote, or immigration hardliner Steve King (R-Iowa) who filed legislation to stop what he calls ?anchor babies? in the first week of this year?s Congress.

Marco Rubio is one politician who seems to have taken notice. Since the Florida senator assumed a prominent role for the GOP on immigration, he appears to have dropped the term ?illegal immigrant? in favor of ?undocumented.?

The Huffington Post adopted the term ?undocumented immigrant? to refer to people in 2008.

Here?s some other suggestions from the Hispanic Leadership Network memo:

When engaging in conversation or doing an interview on immigration reform:

Do acknowledge that ?Our current immigration system is broken and we need to fix it?
Don?t begin with ?We are against amnesty?

When talking about a solution for the millions here without documentation who could qualify to get in line first with a temporary visa, then legal residence and finally citizenship:

Do use the phrase ?earned legal status?
Don?t use the phrase ?pathway to citizenship?

When addressing securing our borders:

Do use the wording ?enforcement of our borders includes more border patrol, technology, and building a fence where it makes sense?
Don?t use phrases like ?send them all back?, ?electric fence?, ?build a wall along the entire border?

When addressing amnesty and earned legal status:

Do acknowledge that the true meaning of amnesty is to pardon without any penalty
Don?t label earned legal status as amnesty
Don?t characterize all Hispanics as undocumented and all undocumented as Hispanics

When broadly addressing reforms:

Do acknowledge that President Obama broke his promise and failed to propose any immigration reform for five years, while using this issue as a political wedge
Do talk about the issues you support like overhauling the bureaucratic visa system, creating a viable temporary worker program, a workable e-verify system, and border security
Don?t focus on amnesty as a tenet of immigration reform
Don't use President Reagan's immigration reform as an example applicable today

Also on HuffPost:

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Source: http://www.huffingtonpost.com/2013/01/30/latino-group-to-politicians-dont-call-immigrants-illegal_n_2581096.html

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